Anti-aging Potential of Extracts Prepared from Fruits and Medicinal Herbs Cultivated in the Gyeongnam Area of Korea
نویسندگان
چکیده
Many recent studies have focused on maintaining a healthy life by preventing and/or postponing the aging process. Numerous studies have reported that continuous exposure to reactive oxygen species can stimulate skin aging and that excessive accumulation of fat can cause an impaired skin barrier and tissue structure alterations. Thus, the maintenance of antioxidant homeostasis and the suppression of adipose accumulation are important strategies for skin anti-aging. Here, we prepared three types of extracts [whole juice, acetone-perchloric acid (PCA), and ethanol] from 20 fruits and medicinal herbs native to the Gyeongnam area of Korea. The total phenolic content of each extract was analyzed, and we observed higher total phenolic contents in the medicinal herbs. Consistent with this, the results of the oxygen radical absorbance activity capacity assay indicated that the in vitro antioxidant activities of the medicinal herb extracts were stronger than those of the fruit extracts. The fruits and medicinal herbs had strong effects on cell-based systems, including H2O2-induced oxidative stress in human keratinocytes and 3T3-L1 lipid accumulation. Nishimura Wase persimmon, Taishu persimmon, wrinkled giant hyssop, sweet wormwood, Chinese cedar, red perilla, tan shen, hiyodori-jogo, and cramp bark may be natural anti-aging materials with effective antioxidant and anti-adipogenic activities. Taken together, our findings may provide scientific evidence supporting the development of functional foods and nutraceuticals from fruits and medicinal herbs.
منابع مشابه
Anti-Aging Effects of Some Selected Iranian Folk Medicinal Herbs-Biochemical Evidences
Objective(s): In the current study, the effects of selected folk medicinal herbs were evaluated in D-galactose-induced aging in male mice. Materials and Methods: Male BALB/c mice were randomly divided into 12 groups composing sham, control, and treated groups. Aging was induced by administration of D-galactose (500 mg/kg/day for 6 weeks). A positive control group was assigned...
متن کاملEvaluation of sun protection activity of some medicinal herbs extracts
In vitro evaluation of sun protection activity of some medicinal herbs by SPF determination, to find out which herbal extracts have the best protection activity and can be used as sunscreen agent. Sun rays are the most environmental harmful factor which affect skin, cause sun burn and photo aging. According to the previous studies the plant’s flavonoids are suitable absorbents for UV rays. In t...
متن کاملEvaluation of sun protection activity of some medicinal herbs extracts
In vitro evaluation of sun protection activity of some medicinal herbs by SPF determination, to find out which herbal extracts have the best protection activity and can be used as sunscreen agent. Sun rays are the most environmental harmful factor which affect skin, cause sun burn and photo aging. According to the previous studies the plant’s flavonoids are suitable absorbents for UV rays. In t...
متن کاملAssessment of Heavy Metal Accumulation and Antibacterial Activity of Some Medicinal Herbs Grown in an Industrial Area of Steel Production, Ahvaz
Unfavorable conditions can affect on secondary metabolites production in the plants. The aim of present study was to evaluate the effect of heavy metals accumulation on antibacterial potential of Chenopodium murale L., Senecio glaucus L., Malva parviflora L. and Calendula arvensis L. grown in an industrial area of steel production in Ahvaz, southwest of Iran. The cadmium (Cd), iron (Fe), mangan...
متن کاملScreening of Korean Medicinal Plant Extracts for α-Glucosidase Inhibitory Activities
Glycosidases are the enzymes involved in various biochemical processes related to metabolic disorders and diseases. Therefore, much effort has been focused on searching novel pharmacotherapy for the treatment of these ailments from medicinal plants due to higher safety margins. To pursue these efforts, the present study was performed to evaluate the α-glucosidase inhibitory activities of thirty...
متن کامل